The UNIKARD Symposium 2014 was held at Gardermoen on November 27. The symposium put emphasis on how scientists can use infrastructure to strengthen their research. The seminar gathered around 50 researchers, mainly Postdocs and Professors, and most of the 18 presentations given are now available in PDF-format below.

The presentations are sorted chronologically, and can be viewed by clicking on the numbered link headlining each topic.

National and European Infrastructure

1. Welcome

Speaker: Charlotte Björk Ingul, UNIKARD

2. European Strategy Forum on Research Infrastructures (ESFRI)

Speaker: Hanne Monclair, Ministry of Education and Research

ESFRI’s objective is to identify and to address the scientific needs of research infrastructures in Europe. Its mission is to support a coherent and strategy-led approach to policy-making on new and existing pan-European and global research infrastructures. ESFRI facilitates multilateral initiatives leading to the better use and development of research infrastructures, acting as an incubator for decision-making processes.

3. Norwegian (NorCRIN) and European Clinical Research Infrastructures Network (ECRIN)

Speaker: Sigrun Kristine Sæther, St. Olavs Hospital

NorCRIN wishes to develop and strengthen the national network of research infrastructure. NorCRIN’s aim is to facilitate clinical research by supporting the many complex elements of this type of research, such as study design, the application process, conduction and GCP reporting (Good Clinical Practice). The main objective is to strengthen and simplify the collaboration within all categories of clinical research in Norway. NorCRIN is the Norwegian part of ECRIN. The Ministry of Health and Care Services in Norway initiated the founding of NorCRIN, and Trondheim University Hospital (St. Olavs Hospital) is responsible for coordinating and operating the network.

ECRIN is a European network dedicated to improving the health of patients and citizens across the world through clinical research. ECRIN supports, services, coordinates, and manages high-quality, independent, and fully transparent multinational clinical research. ECRIN synergizes the capacities and capabilities of national clinical research. ECRIN strives for harmonization of European clinical research. By facilitating clinical research across Europe, ECRIN contributes to the achievement of the ‘European Research Area’ and the ‘society of knowledge’ and adds to European competitiveness.

4. European Advanced Translational Research Infrastructure (EATRIS)

Speaker: Kjetil Taskén, Centre for Molecular Medicine (NCMM)

EATRIS Centre Norway is a Norwegian node for the European Advanced Translational Research Infrastructure in Medicine. Translational medicine is the transformation of laboratory research outcomes into new ways to diagnose and treat patients to improve the health of millions of people worldwide. It takes promising biomedical innovations ‘from bench to bedside’ and bridges clinical needs from bedside to bench. EATRIS provides a new development pathway, open to researchers and companies in need of support for advancing biomedical innovations. EATRIS comprises over 70 leading academic institutions across Europe, each renowned for its individual skills and high-end research facilities.

5. EU-Openscreen and Chemical Biology (included in the EATRIS presentation)

Speaker: Kjetil Taskén, Centre for Molecular Medicine (NCMM)

EU-OPENSCREEN is a European Infrastructure of Open Screening Platforms for Chemical Biology. Building a sustainable European infrastructure for Chemical Biology, supporting life science research and its translation to medicine, agriculture, bioindustries and society. The aim of EU-OPENSCREEN is the discovery of biologically active substances in all areas of the Life Sciences by providing transnational open access to the most advanced technologies, chemical and biological resources, and expertise and harnessing the rich chemistry knowledge of Europe in a common compound collection to advance the elucidation of the molecular mechanisms of complex biological phenomena.

Registries

6. How to use National Cardiovascular Registry for randomized studies

Speaker: Ole Fröbert, SCAAR. Swedeheart

7. National Cardiovascular Registry

Speaker: Marta Ebbing, Norwegian Institute of Public Health

8. Epidemiological registry research – the CVDNOR project

Speaker: Grethe Tell, Norwegian Institute of Public Health

Imaging and Structural Biology

9. Nor-BioImaging  and Euro-BioImaging: part 1/part 2

Speaker: Ole M. Sejersted, University of Oslo

Euro‐BioImaging is a large‐scale pan‐European research infrastructure project on the European Strategy Forum on Research Infrastructures (ESFRI) Roadmap The mission is to build a distributed imaging infrastructure across Europe that will provide open access to innovative biological and medical imaging technologies for European researchers. The project is funded by the EU and currently the consortium is finalizing the basic principles for the operation of future EBI organization.

Nor-BioImaging was established in 2011 as the Norwegian national participant organization towards Euro-BioImaging, and replaced the former NorMIC consortium for advanced light microscopy and molecular imaging.

10. Norwegian Structural Biology Centre (Norstruct)

Speaker: Arne O. Smalås, University of Tromsø

The Norwegian Structural Biology Centre (NorStruct) was established in 2003 as a national laboratory for 3D structural analysis within the functional genomics initiative in Norway (FUGE) The Centre offers consulting, service, courses and collaboration to the Norwegian research community in structural biology techniques. The lab is equipped with state-of-the-art instrumentation for the full pipeline from protein production through high throughput crystallization and structure determination to drug discovery related tasks. The NorStruct facilities and competence are divided into three platforms, «Protein production”» (SP1), «Structure determination» (SP2), and «Drug discovery and design» (SP3), which are available to the Norwegian research community through services and collaborative projects.

Sequencing, Bioinformatics and Biobanks

11. Deep Sequencing: part 1/part 2/part 3

Speaker: Leonardo A. Meza-Zepeda, Oslo University Hospital

The Norwegian Sequencing Centre is a national technology core facility offering sequencing services. Method for sequencing DNA molecules of which is up to several million times more efficient than current dominant method for DNA sequencing. This makes it possible making far more extensive examination of the genome of human, cancer cells and medically relevant microorganisms

12. Bioinformatics

Speaker: Eivind Hovig, Oslo University Hospital

Bioinformatics deals with the analysis of nucleotide and amino acid sequences, and prediction and modelling of protein or RNA structure. Modern bioinformatics includes subjects like analysis of microarray data or simulation of complex interactions between the molecules in a cell. The Norwegian Bioinformatics Platform is a joint project between five partner organisations: the University of Bergen, the University of Oslo, the Norwegian University of Science and Technology in Trondheim, the University of Tromsø and the Norwegian University of Life Sciences at Ås. The platform is coordinated from the Computational Biology Unit at the University of Bergen.

13. Systems Biology: part 1/part 2

Speaker: Molly Maleckar, SIMULA School of Research and Innovation

Systems Biology refers to a type of biological research that is firmly based on a model of a biological system. It aims to use that model to explain and simulate the behaviour of a biological system, and to use simulations to help design experiments to challenge, expand and refine that model. Simula Research Laboratory‘s main objective is to create knowledge about fundamental scientific challenges that are of genuine value for society. Important research with long-term impact in the fields of communication systems, scientific computing and software engineering constitutes the basis of Simula. The strong focus on basic research is combined with both teaching of postgraduate students and development of commercial applications

14. Biobanks

Speaker: Gun Peggy Knudsen, Norwegian Institute of Public Health

Regional Core Facilities

Each presentation provides information of the available core facilities situated at the given locations.

15. Trondheim

Speaker: Janne Østvang, Norwegian University of Science and Technology

16. Bergen

Speaker: Frode Berven, University of Bergen

17. Oslo

Speaker: Ivar Sjaastad, University of Oslo

18. Tromsø

Speaker: Ståle Liljedal, University of Tromsø

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